Question: What is acral peeling skin syndrome?

How do you treat acral peeling?

There is no cure for acral peeling skin syndrome . Treatment is centered on preventing skin damage and addressing symptoms as they occur. Emollients are often used to reduce skin peeling. If blister develop, they may be lanced with a sterile needle.

How do you get peeling skin syndrome?

Peeling skin syndrome is inherited in an autosomal recessive pattern. All individuals inherit two copies of each gene . Autosomal means the gene is found on one of the numbered chromosomes found in both sexes. Recessive means that both copies of the responsible gene must be altered to have the condition.

What does peeling skin syndrome look like?

PSS is characterized by painless, continual, spontaneous skin peeling (exfoliation) due to a separation of the outermost layer of the epidermis (stratum corneum) from the underlying layers. Other findings may include blistering and/or reddening of the skin (erythema) and itching (pruritus).

How many people have acral peeling skin?

Acral PSS is rare, with approximately 40 cases described in the literature to date.

What causes acral peeling?

Acral peeling skin syndrome is caused by mutations in the TGM5 gene. This gene provides instructions for making an enzyme called transglutaminase 5, which is a component of the outer layer of skin (the epidermis).

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How is acral peeling skin diagnosed?

The diagnosis of acral peeling skin syndrome is mainly based on personal history and clinical picture of superficial acral skin peeling and blistering, often exacerbated by heat, maceration and/or minor mechanical trauma.

Is acral peeling skin syndrome painful?

Acral peeling skin syndrome (APSS) is an inheritable skin condition that causes painless peeling of the top layer of skin, typically on the hands or feet. This condition is very rare, and a person’s biological parents must each carry a copy of the gene mutation for a person to show any symptoms.

Is skin peeling normal?

Peeling skin is common and usually part of the healing of skin damage. Superficial loss of skin cells is a normal ongoing process, but noticeable peeling skin can be due to injury or disease.

What immune system disorders cause skin peeling?

Specific diseases and conditions that can cause peeling skin include:

  • Athlete’s foot.
  • Atopic dermatitis (eczema)
  • Contact dermatitis.
  • Cutaneous T-cell lymphoma.
  • Dry skin.
  • Hyperhidrosis.
  • Jock itch.
  • Kawasaki disease.

What deficiency causes skin peeling?

A Vitamin B deficiency can wreak havoc on your skin, causing acne, rashes, dry and flaky skin, cracked lips, and wrinkles.

What infections cause skin peeling?

Peeling skin may arise from infectious diseases, such as:

  • Scarlet fever.
  • Staphylococcal scalded skin syndrome.
  • Tinea infections (Athlete’s foot, jock itch, ringworm)
  • Toxic-shock syndrome (late)