What is perivascular lymphocytic dermatitis?
Microscopically acute GVHD is a vacuolar interface dermatitis characterized by a usually mild superficial perivascular lymphocytic infiltrate with varying amounts of epidermal damage consisting of basal vacuolization and usually some dyskeratotic keratinocytes with satellite cell necrosis (Fig.
What causes perivascular lymphocytic infiltrate?
A prominent perivascular neutrophilic inflammatory cell infiltrate can be associated with neutrophilic urticarial reactions (fig 7A), dermatitis herpetiformis, early IgA dermatosis, early Sweet’s syndrome,26–28 early connective tissue disorders such as lupus erythematosus, early herpetic infection, and acute …
What are inflammatory dermatoses?
Inflammatory dermatoses encompass an enormous area of dermatopathology. These diseases are triggered and maintained by aberrant responses of the cells of the skin immune system.
How do you treat perivascular lymphocytic infiltrate?
A diagnosis of Jessner lymphocytic infiltration of the skin was made. Treatment with intralesional corticosteroids every 4 weeks and oral hydroxychloroquine resulted in resolution after 4 months of therapy, thus far with no recurrence.
What is lymphocytic inflammation?
Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a treatable inflammatory disease of the central nervous system . Specifically, it is a type of encephalomyelitis, which is a general term describing inflammation of the brain and spinal cord.
What causes lymphocytic inflammatory infiltrate?
Lymphocytic Infiltrate of Jessner is a rare inflammatory disease with an unknown cause. What is known however is that this condition involves the inappropriate accumulation of T helper cells (subtype of white blood cells) in the skin.
What is the difference between dermatitis and dermatosis?
Dermatosis refers to several different types of skin conditions. Any irregularity of the skin is considered a dermatosis. If the skin is inflamed, however, the condition is considered dermatitis, not dermatosis. If you suspect that you are experiencing dermatosis, see your dermatologist to be examined.
What is Sweet’s syndrome?
Sweet’s syndrome is an uncommon skin condition marked by a distinctive eruption of tiny bumps that enlarge and are often tender to the touch. They can appear on the back, neck, arms or face. Sweet’s syndrome, also called acute febrile neutrophilic dermatosis, is an uncommon skin condition.
What are inflammatory lesions?
What are inflammatory lesions in acne? Inflammatory lesions in acne include small red bumps (papules), pustules, large red bumps (nodules) and pseudocysts (these are fluctuant nodules). Inflammatory acne lesions are often painful.